SERUM ZINC LEVELS IN SUDANESE PATIENTS WITH ACUTE LYMPHOCYTIC LEUKEMIA

Simple item page
dc.creatorMohamed, Omar W. A.
dc.creatorBakhiet, Sahar M.
dc.creatorGerges, Hani K. F.
dc.creatorKordofani, Anwaar A.Y.
dc.date.accessioned2026-01-10T18:52:45Z
dc.date.available2026-01-10T18:52:45Z
dc.date.issued2017-01-14
dc.descriptionBackground: Zinc acts as growth protector for neoplastic cells and its deficiency was contributed to carcinogenesis. However, the determinations of serum zinc in acute lymphocytic leukemia (ALL) prediction and prognosis requires more investigations. Objective: To evaluate and compare serum zinc in ALL patients and healthy controls and to correlate the serum zinc levels with hematological prognostic markers. Materials and methods: The study was conducted in Khartoum state-Sudan during the period from December 2013 to September 2014, it involved a case group of ALL patients (N=100) matched for age and gender with a control group (N=100). Serum copper and zinc levels and full blood count were investigated. Results: The ALL patients showed lower levels of Zn 0.73 ± 0.18 mg/dl compared to controls 1.01 ± 0.25 mg/dl [P = 0.003]. The serum Zn levels were inversely correlated with total white cell (-0.804, P < 0.0001) and blast counts (-0.935, P < 0.0001). Conclusion: These findings ALL associated with lower serum zinc levels and higher serum copper levels. The determination of serum zinc and copper could be used as ALL prognostic markers. KEYWORDS: Acute lymphoblastic leukemia; Zinc; Carcinogenesis.en-US
dc.formatapplication/pdf
dc.identifierhttps://sumathipublications.com/index.php/ijcbr/article/view/132
dc.identifier.urihttps://repos.sumathipublications.com:8000/handle/123456789/129
dc.languageeng
dc.publisherSumathi Publicationsen-US
dc.relationhttps://sumathipublications.com/index.php/ijcbr/article/view/132/158
dc.relation.ispartofInternational Journal of Clinical and Biomedical Researchen-US
dc.relation.ispartofseriesVolume 3, Issue 1en-US
dc.rightsCopyright (c) 2017 Omar W. A. Mohamed, Sahar M. Bakhiet, Hani K. F. Gerges, Anwaar A.Y. Kordofanien-US
dc.sourceInternational Journal of Clinical and Biomedical Research; Volume 3, Issue 1; January 2017; 18-20en-US
dc.source2395-0471
dc.source2521-0394
dc.titleSERUM ZINC LEVELS IN SUDANESE PATIENTS WITH ACUTE LYMPHOCYTIC LEUKEMIAen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

Files

Collections

International Journal of Clinical and Biomedical Research (IJCBR)