Adverse Reactions Caused by Antiepileptic Medications in Real-World Medical Settings

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dc.creatorAhmad Mir, Mashooq
dc.creatorBashir Malik, Abrar
dc.creatorQadrie, Zulfkar
dc.creatorAltaf Dar, Mohd
dc.date.accessioned2026-01-10T19:04:09Z
dc.date.available2026-01-10T19:04:09Z
dc.date.issued2023-12-10
dc.descriptionEpilepsy is a relatively common condition characterized by a tendency for recurrent seizures, which is due to the disturbance of spread of electrical discharge of the cortical neurons. Up to 80% of people with epilepsy are able to control their condition with anti epileptic drugs (AEDs). The growing number of newly approved drugs for various illnesses coupled with the complex treatment options have contributed to the increased risk of adverse drug reactions (ADRs). AEDs have a narrow therapeutic index with wide spectrum of ADRs. 10-30% of epileptic patients discontinue their initially prescribed AEDs due to ADRs. These ADRs can be the cause of non-adherence and subjective distress. The newer generation AEDs have reduced adverse events, fewer drug interactions if any and thus improved safety. Comparison of adverse effects in patients taking AEDs with adverse events in control groups is helpful; however, data from controlled studies are often lacking for most AEDs. Because of these limitations, the clinician must adopt a preventative and early detection approach based on some general principles. This review outlines   various adverse reactions related to the use of Anti-epileptic drugs. Keywords: adverse reactions, antiepileptic drugs, carbamazepine, phenytoinen-US
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dc.identifierhttps://sumathipublications.com/index.php/ijcrpp/article/view/478
dc.identifier.urihttps://repos.sumathipublications.com:8000/handle/123456789/270
dc.languageeng
dc.publisherSumathi Publicationsen-US
dc.relationhttps://sumathipublications.com/index.php/ijcrpp/article/view/478/624
dc.relationhttps://sumathipublications.com/index.php/ijcrpp/article/view/478/636
dc.relation.ispartofInternational Journal of Current Research in Physiology and Pharmacologyen-US
dc.relation.ispartofseriesVolume 7, Supplement 3en-US
dc.rightsCopyright (c) 2023 Mashooq Ahmad Mir, Abrar Bashir Malik, Zulfkar Qadrie, Mohd Altaf Daren-US
dc.rightshttp://creativecommons.org/licenses/by-nc-sa/4.0en-US
dc.sourceInternational Journal of Current Research in Physiology and Pharmacology; Volume 7, Supplement 3; 2023; 25-35en-US
dc.source2523-6709
dc.source2523-6695
dc.subjectadverse reactions, anti-epileptic drugs, carbamazepine, phenytoinen-US
dc.titleAdverse Reactions Caused by Antiepileptic Medications in Real-World Medical Settingsen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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International Journal of Current Research in Physiology and Pharmacology (IJCRPP)