HEPARIN INDUCED THROMBOCYTOPENIA AND HEMODIALYSIS

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dc.creatorELHASSADE, AMAL S.
dc.creatorNASER, AHLAM MOHAMED BEN
dc.date.accessioned2026-01-10T18:52:43Z
dc.date.available2026-01-10T18:52:43Z
dc.date.issued2016-10-19
dc.descriptionUnfractionated heparin is the most commonly used anticoagulant for hemodialysis (HD).  It is well-known that heparin can cause immune-mediated thrombocytopenia due to immunoglobulin antibody formation against the complex of platelet factor 4 (PF4) and heparin. Heparin may also contribute to HD-associated platelet activation, thrombocytopenia, and increased PF4 release from platelets during a heparin dialytic session. The present study was conducted to study the effect of unfraction heparin as anticoagulant in newly treatment hemodialysis patients. Material and method: A sample of 72 people were selected, 32 patients on dialysis for first time from unite of kidney dialysis. At the same time a group of 40 randomly selected healthy adults to participate in the study as control. By Automated cell counter (sysmex X 21) platelets from all patients on dialysis before starting heparin and after one month later were estimated. Result: The mean value of platelets in patients after treated with heparin was significant lower (192.3 ± 20.7 ) — 109/l as compare before treated with heparin 203 ± 20.7 — 109/l  ( P = 0.001). Conclusion: From this study, heparin as anti-coagulant has effect on decrease platelets count but still patients have no thrombocytopenia platelets level 150 — 109/l.hen-US
dc.formatapplication/pdf
dc.identifierhttps://sumathipublications.com/index.php/ijcbr/article/view/124
dc.identifier.urihttps://repos.sumathipublications.com:8000/handle/123456789/121
dc.languageeng
dc.publisherSumathi Publicationsen-US
dc.relationhttps://sumathipublications.com/index.php/ijcbr/article/view/124/150
dc.relation.ispartofInternational Journal of Clinical and Biomedical Researchen-US
dc.relation.ispartofseriesVolume 2, Issue 4en-US
dc.rightsCopyright (c) 2016 AMAL S. ELHASSADE, AHLAM MOHAMED BEN NASERen-US
dc.sourceInternational Journal of Clinical and Biomedical Research; Volume 2, Issue 4; October 2016; 66-68en-US
dc.source2395-0471
dc.source2521-0394
dc.titleHEPARIN INDUCED THROMBOCYTOPENIA AND HEMODIALYSISen-US
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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